MULTIPLEX IMMUNOFLUORESCENCE AND THE DIGITAL IMAGE ANALYSIS WORKFLOW FOR EVALUATION OF THE TUMOR IMMUNE ENVIRONMENT IN TRANSLATIONAL RESEARCH

Multiplex Immunofluorescence and the Digital Image Analysis Workflow for Evaluation of the Tumor Immune Environment in Translational Research

A robust understanding of the tumor immune environment has important implications for cancer diagnosis, prognosis, research, and immunotherapy.Traditionally, immunohistochemistry (IHC) has been regarded as the standard method for detecting proteins ONION CUBES in situ, but this technique allows for the evaluation of only one cell marker per tissue

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Updated protocol of the SANO trial: a stepped-wedge cluster randomised trial comparing surgery with active surveillance after neoadjuvant chemoradiotherapy for oesophageal cancer

Abstract Background The Surgery As Needed for Oesophageal cancer (SANO) trial compares active surveillance with standard oesophagectomy for patients with a clinically complete response (cCR) to neoadjuvant chemoradiotherapy.The last patient with a clinically complete response is expected to be included in May 2021.The purpose of this update is to p

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